Z-GGF-CMK
Z-GGF-CMK is a protease inhibitor, inhibits ClpP1P2 and proteasome. Z-GGF-CMK exhibits cytotoxic activity against HepG2 cells with a CC50 value of 125 μM[1].
Product Specifications
CAS Number
35172-59-9
UNSPSC
12352209
Target
ClpP; Proteasome
Type
Peptides
Related Pathways
Cell Cycle/DNA Damage; Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/z-ggf-cmk.html
Solubility
10 mM in DMSO
Smiles
O=C(OCC1=CC=CC=C1)NCC(NCC(N[C@H](C(CCl)=O)CC2=CC=CC=C2)=O)=O
Molecular Formula
C22H24ClN3O5
Molecular Weight
445.90
References & Citations
[1]Moreira W, et, al. Bortezomib Warhead-Switch Confers Dual Activity against Mycobacterial Caseinolytic Protease and Proteasome and Selectivity against Human Proteasome. Front Microbiol. 2017 Apr 27;8:746.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Frequently Asked Questions
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