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Z-GGF-CMK

Z-GGF-CMK is a protease inhibitor, inhibits ClpP1P2 and proteasome. Z-GGF-CMK exhibits cytotoxic activity against HepG2 cells with a CC50 value of 125 μM[1].

Product Specifications

CAS Number

35172-59-9

UNSPSC

12352209

Target

ClpP; Proteasome

Type

Peptides

Related Pathways

Cell Cycle/DNA Damage; Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/z-ggf-cmk.html

Solubility

10 mM in DMSO

Smiles

O=C(OCC1=CC=CC=C1)NCC(NCC(N[C@H](C(CCl)=O)CC2=CC=CC=C2)=O)=O

Molecular Formula

C22H24ClN3O5

Molecular Weight

445.90

References & Citations

[1]Moreira W, et, al. Bortezomib Warhead-Switch Confers Dual Activity against Mycobacterial Caseinolytic Protease and Proteasome and Selectivity against Human Proteasome. Front Microbiol. 2017 Apr 27;8:746.

Shipping Conditions

Room temperature

Scientific Category

Peptides

Clinical Information

No Development Reported

Frequently Asked Questions

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