Hydrangenol

Hydrangenol is an orally active antiphotoaging compound. It can be isolated from Hydrangea serrata leaves. Hydrangenol prevents wrinkle formation by reducing MMP and inflammatory cytokine expression and increasing moisturizing factors and antioxidant genes level[1].

Product Specifications

CAS Number

[480-47-7]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

COX; ERK; Interleukin Related; Keap1-Nrf2; MMP; p38 MAPK

Type

Natural Products

Related Pathways

Immunology/Inflammation; MAPK/ERK Pathway; Metabolic Enzyme/Protease; NF-κB; Stem Cell/Wnt

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/hydrangenol.html

Purity

99.63

Solubility

10 mM in DMSO

Smiles

O=C1C2=C(O)C=CC=C2CC(C3=CC=C(O)C=C3)O1

Molecular Formula

C15H12O4

Molecular Weight

256.25

Precautions

H302, H315, H319, H335

References & Citations

[1]Myung DB, et al. Hydrangenol Isolated from the Leaves of Hydrangea serrata Attenuates Wrinkle Formation and Repairs Skin Moisture in UVB-Irradiated Hairless Mice. Nutrients. 2019 Oct 2;11 (10) :2354.