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MNK1/2-IN-5

MNK1/2-IN-5 is a potent and selective MNK1/2 inhibitor as a therapeutic agent.

Product Specifications

CAS Number

[1426928-20-2]

UNSPSC

12352005

Target

MNK

Type

Reference compound

Related Pathways

MAPK/ERK Pathway

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Infection; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/mnk1-2-in-5.html

Purity

99.93

Solubility

DMSO : 7.14 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

NC[C@@H](C)OC1=NN2C(C3=CC4=CC=CC=C4O3)=CN=C2C=C1

Molecular Formula

C17H16N4O2

Molecular Weight

308.33

References & Citations

[1]Xu W, et al. Update on the Development of MNK Inhibitors as Therapeutic Agents. J Med Chem. 2021 Sep 17.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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