7-Hydroxyflavone (Standard)
7-Hydroxyflavone (Standard) is the analytical standard of 7-Hydroxyflavone. This product is intended for research and analytical applications. 7-Hydroxyflavone is a flavonoid isolated from Clerodendrum phlomidis, with anti-inflammatory activity. 7-Hydroxyflavone protects renal cells from nicotine (NIC) -associated cytotoxicity via the ERK/Nrf2/HO-1 pathway. 7-Hydroxyflavone inhibits PKM2 with an IC50 of 2.12 μM. 7-Hydroxyflavone inhibits COX-2 and 5-LOX with IC50 of 27 µg/mL and 33 µg/mL. 7-Hydroxyflavone is orally active[1][2][4].
Product Specifications
CAS Number
6665-86-7
UNSPSC
12352005
Target
Apoptosis; COX; Enterovirus; ERK; Keap1-Nrf2; Lipoxygenase; Pyruvate Kinase; Reference Standards; Virus Protease
Type
Reference Standards
Related Pathways
Anti-infection; Apoptosis; Immunology/Inflammation; MAPK/ERK Pathway; Metabolic Enzyme/Protease; NF-κB; Others; Stem Cell/Wnt
Field of Research
Cancer; Metabolic Disease; Inflammation/Immunology; Neurological Disease; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/7-hydroxyflavone-standard.html
Smiles
O=C1C=C(C2=CC=CC=C2)OC3=CC(O)=CC=C13
Molecular Formula
C15H10O3
Molecular Weight
238.24
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Available Sizes
Frequently Asked Questions
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