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HSD17B13-IN-22

HSD17B13-IN-22 (Compound 18.03) is an inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13) . HSD17B13-IN-22 can be used in the research of liver diseases such as hepatitis, liver fibrosis, liver cirrhosis, and hepatocellular carcinoma[1].

Product Specifications

CAS Number

[2919797-60-5]

UNSPSC

12352005

Target

17β-HSD

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/hsd17b13-in-22.html

Solubility

10 mM in DMSO

Smiles

COC[C@@H]1CN(CCN1C2=NC3=C(C(C4=CC(C(F)(F)F)=C(C(O)=C4F)F)=NN3C)C=N2)S(C)(=O)=O

Molecular Formula

C20H21F5N6O4S

Molecular Weight

536.48

References & Citations

[1]Johnny Y. Nagasawa, et al. Hsd17b13 inhibitors and uses thereof. WIPO, WO2023043836A1. 2023-03-23.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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