Crotamiton

Crotamiton is a drug that is used both as a scabicidal (for treating scabies) and as a general antipruritic. It is a prescription lotion based medicine that is applied to the whole body to get rid of the scabies parasite.

Product Specifications

CAS Number

[483-63-6]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Parasite

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/Crotamiton.html

Purity

98.07

Solubility

DMSO : 140 mg/mL (ultrasonic) |H2O : 140 mg/mL (ultrasonic)

Smiles

C/C=C/C(N(CC)C1=CC=CC=C1C)=O

Molecular Formula

C13H17NO

Molecular Weight

203.28

Precautions

H302, H315, H319, H335

References & Citations

[1]Kittaka H, et al. Transient receptor potential vanilloid 4 (TRPV4) channel as a target of crotamiton and its bimodal effects. Pflugers Arch. 2017 Oct;469 (10) :1313-1323.