VSW1198
Product Specifications
UNSPSC Description
VSW1198 is an inhibitor for geranylgeranyl diphosphate synthase (GGDPS) with an IC50 of 45 nM. VSW1198 reveals antitumor activity in myeloma- and prostate cancer with liver toxicity[1].
Target Antigen
Others
Type
Reference compound
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/vsw1198.html
Solubility
10 mM in DMSO
Smiles
O=P(O[Na])(O[Na])C(P(O[Na])(O[Na])=O)CC1=CN(CC/C=C(C)/CC/C=C(C)/C)N=N1
Molecular Weight
495.27
References & Citations
[1]Haney SL, Varney ML, Chhonker Y, Talmon G, Smith LM, Murry DJ, Holstein SA. In vivo evaluation of combination therapy targeting the isoprenoid biosynthetic pathway. Pharmacol Res. 2021 May;167:105528.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-111636/VSW1198-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-111636/
Clinical Information
No Development Reported
Curated Selection
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