Interleukin-17RA/CD217 Extracellular Domain

<strong>Interleukin-17RA/CD217 Extracellular Domain</strong>_x000D_ <strong>Catalog number:</strong> B2016878_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 50 µg_x000D_ <strong>Molecular Weight or Concentration:</strong> 62 kDa_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -80°C_x000D_ <strong>Keywords:</strong> CDw217, IL-17 Receptor A, Interleukin-17 Receptor A_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Navrazhina K, Frew JW, Grand D, Williams SC, Hur H, Gonzalez J, Garcet S, Krueger JG. Interleukin-17RA blockade by brodalumab decreases inflammatory pathways in hidradenitis suppurativa skin and serum Br J Dermatol. 2022 Aug;187(2):223-233._x000D_ 2: Scheel CH, Rached NA, Gambichler T. Interleukin-17RA blockade by brodalumab decreases inflammatory pathways in hidradenitis suppurativa skin and serum Br J Dermatol. 2022 Aug;187(2):138-139._x000D_ 3: Ghali JR, O'Sullivan KM, Eggenhuizen PJ, Holdsworth SR, Kitching AR. Interleukin-17RA Promotes Humoral Responses and Glomerular Injury in Experimental Rapidly Progressive Glomerulonephritis Nephron. 2017;135(3):207-223._x000D_ 4: Chai BY, Yip WK, Dusa N, Mohtarrudin N, Seow HF. Loss of Interleukin-17RA Expression is Associated with Tumour Progression in Colorectal Carcinoma Pathol Oncol Res. 2020 Oct;26(4):2291-2298._x000D_ 5: Jiang JK, Lin CH, Chang TA, Lo LC, Lin CP, Lu RH, Yang CY. Decreased interleukin-17RA expression is associated with good prognosis in patients with colorectal cancer and inhibits tumor growth and vascularity in mice Cancer Med. 2024 Mar;13(5):e7059._x000D_ 6: Yu Y, Weiss RM, Wei SG. Brain Interleukin-17A contributes to neuroinflammation and cardiac dysfunction in rats with myocardial infarction Front Neurosci. 2022 Oct 13;16:1032434._x000D_ 7: Chen Y, Zhong M, Liang L, Gu F, Peng H. Interleukin-17 induces angiogenesis in human choroidal endothelial cells in vitro Invest Ophthalmol Vis Sci. 2014 Sep 16;55(10):6968-75._x000D_ 8: Fargnoli MC, Bardazzi F, Bianchi L, Dapavo P, Fabbrocini G, Gisondi P, Micali G, Offidani AM, Pellacani G, Skroza N, Angileri RG, Burlando M, Campanati A, Carrera CG, Chiricozzi A, Conti A, Simone C, Di Lernia V, Errichetti E, Galluzzo M, Guarneri C, Lasagni C, Lembo S, Loconsole F, Megna M, Musumeci ML, Prignano F, Richetta AG, Trovato E, Venturini M, Peris K, Pinton PC. Brodalumab for the Treatment of Moderate-to-Severe Psoriasis: An Expert Delphi Consensus Statement J Clin Med. 2023 May 18;12(10):3545._x000D_ 9: Freches D, Korf H, Denis O, Havaux X, Huygen K, Romano M. Mice genetically inactivated in interleukin-17A receptor are defective in long-term control of Mycobacterium tuberculosis infection Immunology. 2013 Oct;140(2):220-31._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/27594156">10: Xu ZZ, Sun CY, Xie LZ. Preparation and Activity Detection of A Novel Monoclonal Antibody to Human Interleukin-17RA Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2016 Aug;38(4):428-33. </a>_x000D_ _x000D_ <strong>Products Related to Interleukin-17RA/CD217 Extracellular Domain can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>