GW549390X
Product Specifications
UNSPSC Description
GW549390X is a dual inhibitor of Fluc and VEGFR2 with IC50 of 0.26 μM and 1.2 μM, respectively. GW549390X can bind to the ATP pocket of FLuc through the aniline side chain and is an ATP-competitive inhibitor of Fluc. GW549390X acts as a protein kinase inhibitor across ATP-dependent and -independent luciferases, with potential implications for Fluc reporter assays[1].
Target Antigen
VEGFR
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/gw549390x.html
Solubility
10 mM in DMSO
Smiles
C1(NC2=NC=C(C3=CC=CC=C3)O2)=CC=CC=C1
Molecular Weight
236.27
References & Citations
[1]Dranchak P, et al. Profile of the GSK published protein kinase inhibitor set across ATP-dependent and-independent luciferases: implications for reporter-gene assays. PLoS One. 2013;8(3):e57888.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-160687/GW549390X-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-160687/
Clinical Information
No Development Reported
CAS Number
135307-33-4
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS1296210 Inquire
Recombinant Caenorhabditis briggsae Probable elongator complex protein 3 (elpc-3), partial
Ask
View Details 
