HJC0350
HJC0350 is a potent and specific EPAC2 antagonist with an IC50 of 0.3 μM.
Product Specifications
CAS Number
[885434-70-8]
UNSPSC
12352005
Hazard Statement
H302, H319, H332, H372, H400
Target
Ras
Type
Reference compound
Related Pathways
GPCR/G Protein; MAPK/ERK Pathway
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/HJC0350.html
Purity
98.11
Solubility
DMSO : 33.33 mg/mL (ultrasonic)
Smiles
O=S(N1C(C)=CC(C)=C1)(C2=C(C)C=C(C)C=C2C)=O
Molecular Formula
C15H19NO2S
Molecular Weight
277.38
Precautions
H302, H319, H332, H372, H400
References & Citations
[1]Chen H, et al. Identification and characterization of small molecules as potent and specific EPAC2 antagonists. J Med Chem. 2013 Feb 14;56 (3) :952-62.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
304721-01 50 µL
ACYP1 (ACYP1, ACYPE, Acylphosphatase-1, Acylphosphatase, erythrocyte isozyme, Acylphosphatase, organ-common type isozyme, Acylphosphate phosphohydrolase 1)
Ask
View Details 
304721-02 100 µL
ACYP1 (ACYP1, ACYPE, Acylphosphatase-1, Acylphosphatase, erythrocyte isozyme, Acylphosphatase, organ-common type isozyme, Acylphosphate phosphohydrolase 1)
Ask
View Details 
MBS6377838-01 0.1 mL
F11 (Coagulation Factor XI, FXI, Plasma Thromboplastin Antecedent, PTA, MGC141891) (MaxLight 405)
Ask
View Details MBS6377838-02 5x 0.1 mL
F11 (Coagulation Factor XI, FXI, Plasma Thromboplastin Antecedent, PTA, MGC141891) (MaxLight 405)
Ask
View Details P9054-63D-AP 100 µL
Prostate Specific Membrane Antigen (PSMA, PSM, Cell Growth-inhibiting Gene 27 Protein, Folate Hydrolase 1, FOLH1, FOLH, Folylpoly gamma Glutamate Carboxypeptidase, FGCP, GIG27, Glutamate Carboxypeptidase 2, GCP2, Glutamate Carboxypeptidase II, GCPII, Membrane Glutamate Carboxypeptidase, mGCP, N-acetylated-alpha-linked Acidic Dipeptidase I, NAALADase I, NAALAD1, Pteroylpoly gamma Glutamate Carboxypeptidase) (AP) discontinued
Ask
View Details