(S) -Mevalonic acid

(S) -Mevalonic acid is the isomer of Mevalonic acid (HY-113071) . Mevalonic acid ((S) -DCIT) is a precursor substance of the mevalonate pathway, which is essential for cell growth and proliferation. Mevalonic acid is effective in inhibiting Simvastatin (HY-17502) -induced decrease in C2C12 cell viability in vitro. Mevalonic acid can be used in studies of myopathy and heart failure[1][2].

Product Specifications

CAS Number

[32451-23-3]

Product Name Alternative

(S) -MVA

UNSPSC

12352211

Hazard Statement

H302-H312-H332

Target

Endogenous Metabolite

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease; Neurological Disease; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/s-mevalonic-acid.html

Smiles

O=C(O)C[C@@](C)(O)CCO

Molecular Formula

C6H12O4

Molecular Weight

148.16

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P363-P501

References & Citations

[1]Moschetti A, et al. Coenzyme Q nanodisks counteract the effect of statins on C2C12 myotubes. Nanomedicine. 2021 Oct;37:102439. |[2]Soma MR, et al. Cholesterol and mevalonic acid modulation in cell metabolism and multiplication. Toxicol Lett. 1992 Dec;64-65 Spec No:1-15.