AL 8810 methyl ester

AL 8810 methyl ester is a prostaglandin F (2α) analog and a prostaglandin F (2α) receptor agonist. Can competitively antagonize the effects of the FP receptor agonist Fluprostenol (HY-108560) . AL 8810 methyl ester has no significant potency against TP, DP, EP (2), EP (4) receptor subtypes in cell lines[1].

Product Specifications

CAS Number

[1176541-11-9]

UNSPSC

12352005

Hazard Statement

H315-H319-H335

Target

Prostaglandin Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Endocrinology

Assay Protocol

https://www.medchemexpress.com/al-8810-methyl-ester.html

Solubility

10 mM in DMSO

Smiles

O[C@H](C1CC2=CC=CC=C2C1)/C=C/[C@@H]3[C@H]([C@H](C[C@@H]3F)O)C/C=C\CCCC(OC)=O

Molecular Formula

C25H33FO4

Molecular Weight

416.53

Precautions

P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P362+P364-P403+P233-P405-P501

References & Citations

[1]Griffin BW, et al. AL-8810: a novel prostaglandin F2 alpha analog with selective antagonist effects at the prostaglandin F2 alpha (FP) receptor. J Pharmacol Exp Ther. 1999 Sep;290 (3) :1278-84.