Aflatoxin B1-13C17
Product Specifications
UNSPSC Description
Aflatoxin B1-13C17 is 13C- and 15N-labeled Aflatoxin B1 (HY-N6615). Aflatoxin B1 (AFB1) is a Group 1A carcinogen and a secondary metabolite produced by Aspergillus flavus and Aspergillus parasiticus. Aflatoxin B1 (AFB1) primarily induces mutations by causing a G to T transversion at the third nucleotide of codon 249 in the tumor suppressor gene p53. In the body, Aflatoxin B1 (AFB1) can cause damage to the intestines and kidneys and has some teratogenic effects[1].
Target Antigen
Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Purity
99.90
Solubility
10 mM in DMSO
Smiles
[13CH3]O[13C]1=[13CH][13C]2=[13C]([13C@@]3([H])[13C@@](O[13CH]=[13CH]3)([H])O2)[13C](O4)=[13C]1[13C]([13CH2][13CH2][13C]5=O)=[13C]5[13C]4=O
Molecular Weight
329.15
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.
Shipping Conditions
Blue Ice
Storage Conditions
Solution, -20°C, protect from light, 2 years
Clinical Information
No Development Reported
CAS Number
1217449-45-0
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