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[KO] Integrin alpha V Rabbit mAb

The alpha-V (ITGAV) integrins are receptors for vitronectin, cytotactin, fibronectin, fibrinogen, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin and vWF. They recognize the sequence R-G-D in a wide array of ligands. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions

Product Specifications

Product Name Alternative

ITGAV; MSK8; VNRA; Integrin alpha-V; Vitronectin receptor subunit alpha; CD antigen CD51

UniProt

P06756

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human Integrin alpha V

Target

ITGAV

Clonality

Monoclonal

Clone

BT25X8G5

Conjugation

Unconjugated

Field of Research

Cardiovascular Research

Purification

Affinity Purified

Concentration

0.3 mg/ml

Dilution

WB: 1/500-1/1000 IHC: 1/50-1/100

Form

Liquid

Molecular Weight

Calculated MW: 116 kDa; Observed MW: 135 kDa

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Notes

For research use only.

Tested Applications

IHC-P, WB

Preservative

50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% rAlbumin.

Isotype

IgG

Available Sizes

Frequently Asked Questions

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