Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Buformin-d9 (hydrochloride)

Buformin-d9 (hydrochloride) is the deuterium labeled Buformin. Buformin (1-Butylbiguanide), a potent AMPK activator, acts as an orally active biguanide antidiabetic agent. Buformin decreases hepatic gluconeogenesis and lowers blood glucose production in vivo. Buformin also has anti-cancer activities and is applied in cancer study (such as, cervical cancer and breast cancer, et al) [1].

Product Specifications

Product Name Alternative

1-Butylbiguanide-d9 (hydrochloride)

UNSPSC

12352211

Target

AMPK; Isotope-Labeled Compounds

Type

Isotope-Labeled Compounds

Related Pathways

Epigenetics; Others; PI3K/Akt/mTOR

Field of Research

Cancer; Metabolic Disease

Solubility

10 mM in DMSO

Smiles

N=C(N)NC(NC([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])[2H])=N.[H]Cl

Molecular Formula

C6H7D9ClN5

Molecular Weight

202.73

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]Amanda B Parris, et al. Buformin Inhibits the Stemness of erbB-2-overexpressing Breast Cancer Cells and Premalignant Mammary Tissues of MMTV-erbB-2 Transgenic Mice. J Exp Clin Cancer Res|[3]Jing Li, et al. Buformin Suppresses Proliferation and Invasion via AMPK/S6 Pathway in Cervical Cancer and Synergizes With Paclitaxel. Cancer Biol Ther. 2018 Jun 3;19 (6) :507-517.

Shipping Conditions

Room temperature

Scientific Category

Isotope-Labeled Compounds

Clinical Information

No Development Reported

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

Human Growth Factor Receptor Bound Protein 2 (Grb2) ELISA Kit
RD-Grb2-Hu-01 96 Tests

Human Growth Factor Receptor Bound Protein 2 (Grb2) ELISA Kit

Sign In for Pricing
View Details
Human Growth Factor Receptor Bound Protein 2 (Grb2) ELISA Kit
RD-Grb2-Hu-02 48 Tests

Human Growth Factor Receptor Bound Protein 2 (Grb2) ELISA Kit

Sign In for Pricing
View Details
c-Myc (MYC) pThr358 Rabbit Polyclonal Antibody
AP02336PU-N 100 µL

c-Myc (MYC) pThr358 Rabbit Polyclonal Antibody

Sign In for Pricing
View Details
Mouse Terf2ip activation kit by CRISPRa
GA206165 1 Kit

Mouse Terf2ip activation kit by CRISPRa

Sign In for Pricing
View Details
Tissue FFPE Sections, Meninges
CS712647 5x 5 µm

Tissue FFPE Sections, Meninges

Sign In for Pricing
View Details
MALT1 (MALT-Lymphoma Marker) (MT1/3159R), CF640R conjugate, 0.1mg/mL
BNC403159-500 1x 500 µL

MALT1 (MALT-Lymphoma Marker) (MT1/3159R), CF640R conjugate, 0.1mg/mL

Sign In for Pricing
View Details