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Human PD-1 (Luc) Jurkat Reporter Cell

Human PD-1 (Luc) Jurkat Reporter Cell is expressed from Human Jurkat.

Product Specifications

Background

Programmed cell death protein 1 (PD-1) is also known as CD279 and PDCD1, is a type I membrane protein and is a member of the extended CD28/CTLA-4 family of T cell regulators. PDCD1 is expressed on the surface of activated T cells, B cells, macrophages, myeloid cells and a subset of thymocytes. PD1 inhibits the T-cell proliferation and production of related cytokines including IL-1, IL-4, IL-10 and IFN-γ by suppressing the activation and transduction of PI3K/AKT pathway.

Host

Jurkat

Origin Species

Human

Target

PD-1

Tag

Luc

Applications

• Screen for anti-human PD-1 antagonistic antibody or anti-human PD-L1 antibody. • Screen for anti-human PD-1 agonistic antibody.

Format

Liquid

Additionnal Information

Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/support/shipping-and-payments

Shipping Conditions

Dry ice

Storage Conditions

Frozen in liquid nitrogen

Package Size

1Vial*2

Host or Source

Jurkat

Species

Human

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