URAT1 inhibitor 10
URAT1 inhibitor 10 (Compound 23a) is a URAT1 inhibitor. URAT1 inhibitor 10 has oral efficacy and low cytotoxicity. URAT1 inhibitor 10 has high selectivity for OAT1 [1].
Product Specifications
CAS Number
3012586-38-5
UNSPSC
12352005
Target
URAT1
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/urat1-inhibitor-10.html
Solubility
10 mM in DMSO
Smiles
O=C(N1[C@@H](CCC1)CNS(C(F)(F)F)(=O)=O)C2=CC=NC3=C2C=C(C4CC4)C=C3
Molecular Formula
C19H20F3N3O3S
Molecular Weight
427.44
References & Citations
[1]Li S et al. Proline-derived quinoline formamide compounds as human urate transporter 1 inhibitors with potent uric acid-lowering activities. Eur J Med Chem. 2024 Apr 5;269:116327
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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