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Roxatidine (Standard)

Roxatidine (Standard) is the analytical standard of Roxatidine. This product is intended for research and analytical applications. Roxatidine is an active metabolite of Roxatidine acetate hydrochloride, is a histamine H2-receptor antagonist. Roxatidine, an anti-ulcer agent, suppresses histamine release (thus inhibiting proton secretion) and inhibits the production of VEGF-1, an important marker of inflammation and angiogenesis. Anti-allergic inflammatory effect[1].

Product Specifications

CAS Number

[78273-80-0]

UNSPSC

12352005

Target

Histamine Receptor; Reference Standards

Type

Reference Standards

Related Pathways

GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling; Others

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/roxatidine-standard.html

Smiles

O=C(NCCCOC1=CC=CC(CN2CCCCC2)=C1)CO

Molecular Formula

C17H26N2O3

Molecular Weight

306.40

References & Citations

[1]Lee M, et al. Roxatidine attenuates mast cell-mediated allergic inflammation via inhibition of NF-κB and p38 MAPK activation. Sci Rep. 2017;7:41721. Published 2017 Jan 31.

Shipping Conditions

Room temperature

Scientific Category

Reference Standards

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