Diprotin A

<strong>Diprotin A</strong> <strong>Catalog number:</strong> MDP0501 <strong>CAS Number: </strong>120928-04-3 <strong>Sequence: </strong>Ile-Pro-Ile . H2O <strong>Amount:</strong> 10 mg <strong>Molecular Weight:</strong> 341.2 g/mol <strong>Supplied as:</strong> Powder <strong>Applications:</strong> molecular tool for various biochemical applications <strong>Storage:</strong> -20 °C <strong>WARNING:</strong> For in vitro Research Use Only. NOT for use on humans or animals. <strong>Grade:</strong> Biotechnology grade. All products are highly pure. <strong>References:</strong> 1: Zhou MY, Zhang YJ, Ding HM, Wu WF, Cai WW, Wang YQ, Geng DQ. Diprotin A TFA Exerts Neurovascular Protection in Ischemic Cerebral Stroke Front Neurosci. 2022 May 9;16:861059. 2: Rónai AZ, Timár J, Makó E, Erdö F, Gyarmati Z, Tóth G, Orosz G, Fürst S, Székely JI. Diprotin A, an inhibitor of dipeptidyl aminopeptidase IV(EC 3.4.14.5) produces naloxone-reversible analgesia in rats Life Sci. 1999;64(2):145-52. 3: Rahfeld J, Schierhorn M, Hartrodt B, Neubert K, Heins J. Are diprotin A (Ile-Pro-Ile) and diprotin B (Val-Pro-Leu) inhibitors or substrates of dipeptidyl peptidase IV? Biochim Biophys Acta. 1991 Jan 29;1076(2):314-6. 4: Khlebnikova NN, Orshanskaya EV, Narkevich VB, Kudrin VS, Krupina NA. Dipeptidyl Peptidase 4 Inhibitors Diprotin A and Sitagliptin Administered on Weeks 2-3 of Postnatal Development Modulate Monoamine Metabolism in the Striatum of Adult Rats Bull Exp Biol Med. 2017 Jun;163(2):190-194. 5: Balogh M, Varga BK, Karádi DÁ, Riba P, Puskár Z, Kozsurek M, Al-Khrasani M, Király K. Similarity and dissimilarity in antinociceptive effects of dipeptidyl-peptidase 4 inhibitors, Diprotin A and vildagliptin in rat inflammatory pain models following spinal administration Brain Res Bull. 2019 Apr;147:78-85. 6: Bagosi Z, Jászberényi M, Bujdosó E, Szabó G, Telegdy G. The effects of endomorphins and diprotin A on striatal dopamine release induced by electrical stimulation-an in vitro superfusion study in rats Neurochem Int. 2006 Dec;49(7):665-8. 7: Krupina NA, Khlebnikova NN, Orlova IN. [Emotional Motivational Disorders in Rats as a Result of Diprotin A and Sitagliptin Administration in the First Postnatal Week] Zh Vyssh Nerv Deiat Im I P Pavlova. 2016 May;66(3):367-381. 8: Kawai T, Choi U, Liu PC, Whiting-Theobald NL, Linton GF, Malech HL. Diprotin A infusion into nonobese diabetic/severe combined immunodeficiency mice markedly enhances engraftment of human mobilized CD34+ peripheral blood cells Stem Cells Dev. 2007 Jun;16(3):361-70. 9: Hiramatsu H, Yamamoto A, Kyono K, Higashiyama Y, Fukushima C, Shima H, Sugiyama S, Inaka K, Shimizu R. The crystal structure of human dipeptidyl peptidase IV (DPPIV) complex with diprotin A Biol Chem. 2004 Jun;385(6):561-4. <a href="https://pubmed.ncbi.nlm.nih.gov/24809328">10: Chakraborty C, Hsu MJ, Agoramoorthy G. Understanding the molecular dynamics of type-2 diabetes drug target DPP-4 and its interaction with Sitagliptin and inhibitor Diprotin-A Cell Biochem Biophys. 2014 Nov;70(2):907-22. </a> <br><strong>Products Related to Diprotin A can be found at</strong> <a href="https://moleculardepot.com/product-category/Peptides/"> Peptides</a>