7-Deaza-2'-deoxy-7-iodoadenosine

7-Deaza-2'-deoxy-7-iodoadenosine is an important deoxynucleoside that can be used in the synthesis of other active compounds[1][2].

Product Specifications

CAS Number

[166247-63-8]

UNSPSC

12352200

Hazard Statement

H302, H315, H319, H335

Target

DNA/RNA Synthesis

Type

Biochemical Assay Reagents

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/7-deaza-2-deoxy-7-iodoadenosine.html

Purity

99.71

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

NC1=NC=NC2=C1C(I)=CN2[C@H]3C[C@H](O)[C@@H](CO)O3

Molecular Formula

C11H13IN4O3

Molecular Weight

376.15

Precautions

H302, H315, H319, H335

References & Citations

[1]Frank Seela, et al. Oligonucleotides Containing 7‐Deazaadenines: The Influence of the 7‐Substituent Chain Length and Charge on the Duplex Stability. Research Article|[2]Seela F, et al. DNA containing side chains with terminal triple bonds: Base-pair stability and functionalization of alkynylated pyrimidines and 7-deazapurines. Chem Biodivers. 2006 May;3 (5) :509-14.