LasR agonist 1
LasR agonist 1 (9) is a LasR agonist, with an EC50 of 0.7 μM. Used for P. aeruginosa research[1].
Product Specifications
UNSPSC
12352005
Target
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/lasr-agonist-1.html
Solubility
10 mM in DMSO
Smiles
COC1=C(C=C(C=C1)C(NCC2=NN=C3C=CC(C4=CC=CS4)=CN32)=O)F
Molecular Formula
C19H15FN4O2S
Molecular Weight
382.41
References & Citations
[1]Daniel E Manson, et al. Abiotic Small Molecule Inhibitors and Activators of the LasR Quorum Sensing Receptor in Pseudomonas aeruginosa with Potencies Comparable or Surpassing N-Acyl Homoserine Lactones. ACS Infect Dis. 2024 Apr 12;10 (4) :1212-1221.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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