Human FKHR Protein

<strong>Human FKHR Protein</strong>_x000D_ <strong>Catalog number:</strong> B2013882_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 100 ug_x000D_ <strong>Molecular Weight or Concentration:</strong> 105 kDa_x000D_ <strong>Supplied as:</strong> N/A_x000D_ <strong>Applications:</strong> molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> −20°C_x000D_ <strong>Keywords:</strong> FKHR Protein_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Li R, Erdamar S, Dai H, Wheeler TM, Frolov A, Scardino PT, Thompson TC, Ayala GE. Forkhead protein FKHR and its phosphorylated form p-FKHR in human prostate cancer Hum Pathol. 2007 Oct;38(10):1501-7._x000D_ 2: Puigserver P, Rhee J, Donovan J, Walkey CJ, Yoon JC, Oriente F, Kitamura Y, Altomonte J, Dong H, Accili D, Spiegelman BM. Insulin-regulated hepatic gluconeogenesis through FOXO1-PGC-1alpha interaction Nature. 2003 May 29;423(6939):550-5._x000D_ 3: Scheidler S, Fredericks WJ, Rauscher FJ 3rd, Barr FG, Vogt PK. The hybrid PAX3-FKHR fusion protein of alveolar rhabdomyosarcoma transforms fibroblasts in culture Proc Natl Acad Sci U S A. 1996 Sep 3;93(18):9805-9._x000D_ 4: del Peso L, Gonzlez VM, Hernndez R, Barr FG, Nez G. Regulation of the forkhead transcription factor FKHR, but not the PAX3-FKHR fusion protein, by the serine/threonine kinase Akt Oncogene. 1999 Dec 2;18(51):7328-33._x000D_ 5: Fredericks WJ, Galili N, Mukhopadhyay S, Rovera G, Bennicelli J, Barr FG, Rauscher FJ 3rd. The PAX3-FKHR fusion protein created by the t(2;13) translocation in alveolar rhabdomyosarcomas is a more potent transcriptional activator than PAX3 Mol Cell Biol. 1995 Mar;15(3):1522-35._x000D_ 6: Miller PJ, Hollenbach AD. The oncogenic fusion protein Pax3-FKHR has a greater post-translational stability relative to Pax3 during early myogenesis Biochim Biophys Acta. 2007 Oct;1770(10):1450-8._x000D_ 7: Lu H, Qin J, Wang Z. Pleural Alveolar Rhabdomyosarcoma Clin Lab. 2017 Oct 1;63(10):1745-1748._x000D_ 8: Sublett JE, Jeon IS, Shapiro DN. The alveolar rhabdomyosarcoma PAX3/FKHR fusion protein is a transcriptional activator Oncogene. 1995 Aug 3;11(3):545-52._x000D_ 9: Scheimann AO, Durham SK, Suwanichkul A, Snuggs MB, Powell DR. Role of three FKHR phosphorylation sites in insulin inhibition of FKHR action in hepatocytes Horm Metab Res. 2001 Nov;33(11):631-8._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/7624119">10: Bennicelli JL, Fredericks WJ, Wilson RB, Rauscher FJ 3rd, Barr FG. Wild type PAX3 protein and the PAX3-FKHR fusion protein of alveolar rhabdomyosarcoma contain potent, structurally distinct transcriptional activation domains Oncogene. 1995 Jul 6;11(1):119-30.</a>_x000D_ _x000D_ <strong>Products Related to Human FKHR Protein can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>