Conantokin-T
Product Specifications
UNSPSC Description
Conantokin-T is a γ-carboxyglutamate-containing, N-methyl-D-aspartate (NMDA) antagonist peptidewith an IC50 value of 2 μM. Conantokin-T inhibits NMDA receptor-mediated calcium influx in central nervous system neurons. Conantokin-T can be purified from the venom of the fish-hunting cone snail, Conus tulipa[1].
Target Antigen
iGluR
Type
Peptides
Related Pathways
Membrane Transporter/Ion Channel;Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/conantokin-t.html
Solubility
10 mM in DMSO
Smiles
OC(C=C1)=CC=C1C[C@@H](C(N[C@@H](CCC(N)=O)C(N[C@@H](CCCCN)C(N[C@@H](CCSC)C(N[C@@H](CC(C)C)C(N[C@@H](CC(C(O)=O)C(O)=O)C(N[C@@H](CC(N)=O)C(N[C@@H](CC(C)C)C(N[C@@H](CCCNC(N)=N)C(N[C@H](C(N[C@@H](C)C(N[C@@H](CCC(O)=O)C(N[C@@H](C(C)C)C(N[C@@H](CCCCN)C(N[C@@H](CCCCN)C(N[C@@H](CC(N)=O)C(N[C@@H](C)C(N)=O)=O)=O)=O)=O)=O)=O)=O)CC(C(O)=O)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)NC([C@H](CC(C(O)=O)C(O)=O)NC([C@H](CC(C(O)=O)C(O)=O)NC([C@H](CCC(O)=O)NC(CN)=O)=O)=O)=O
Molecular Weight
2683.81
References & Citations
[1]J A Haack, et al. Conantokin-T. A gamma-carboxyglutamate containing peptide with N-methyl-d-aspartate antagonist activity. J Biol Chem. 1990 Apr 15;265(11):6025-9.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-P1287/Conantokin-T-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-P1287/
Clinical Information
No Development Reported
CAS Number
127476-26-0
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
