NY-ESO-1 (87-111)
Product Specifications
UNSPSC Description
NY-ESO-1 (87-111) is a pan-MHC class II-restricted peptide sequence. NY-ESO-1 (87-111) binds to multiple HLA-DR and HLA-DP4 molecules, and stimulates Th1-type and Th-2/Th0-type CD4+ T cells when presented in the context of HLA-DR and HLA-DP4 molecules[1].
Target Antigen
Others
Type
Peptides
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ny-eso-1-87-111.html
Solubility
H2O
Smiles
OC(C=C1)=CC=C1C[C@H](NC([C@@H](NC([C@H](CCC(O)=O)NC([C@H](CC(C)C)NC([C@@H](N)CC(C)C)=O)=O)=O)CC2=CC=CC=C2)=O)C(N[C@@H](CC(C)C)C(N[C@@H](C)C(N[C@@H](CCSC)C(N3[C@@H](CCC3)C(N[C@H](C(N[C@@H](C)C(N[C@@H]([C@H](O)C)C(N4[C@@H](CCC4)C(N[C@@H](CCSC)C(N[C@@H](CCC(O)=O)C(N[C@@H](C)C(N[C@@H](CCC(O)=O)C(N[C@@H](CC(C)C)C(N[C@@H](C)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CO)C(N[C@@H](CC(C)C)C(N[C@@H](C)C(N[C@H](C(O)=O)CCC(N)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)CC5=CC=CC=C5)=O)=O)=O)=O)=O
Molecular Weight
2869.40
References & Citations
[1]Maja Mandic, et al. One NY-ESO-1-derived epitope that promiscuously binds to multiple HLA-DR and HLA-DP4 molecules and stimulates autologous CD4+ T cells from patients with NY-ESO-1-expressing melanoma. J Immunol. 2005 Feb 1;174(3):1751-9.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-P2507/NY-ESO-1-87-111-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-P2507/
Clinical Information
No Development Reported
CAS Number
508230-31-7
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