OATD-01
OATD-01 is a highly potent, first-in-class, orally active and selective chitinase inhibitor with low nanomolar activity toward CHIT1 (hCHIT1, IC50=23 nM) . OATD-01 shows excellect PK profile in multiple species and is selectivity against a panel of other off-targets. OATD-01 exhibits significant antifibrotic efficacy in vivo and can be used for pulmonary fibrosis (IPF) research[1].
Product Specifications
CAS Number
[2088453-21-6]
UNSPSC
12352005
Target
Others
Type
Reference compound
Related Pathways
Others
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/oatd-01.html
Purity
99.94
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
NC1=NNC(N2CCC(N3C[C@H](C)OC[C@@H]3CC4=CC=C(Cl)C=C4)CC2)=N1
Molecular Formula
C19H27ClN6O
Molecular Weight
390.91
References & Citations
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
Phase 2
Available Sizes
Explore Other Products
Browse additional items from our catalog
TSPY1 (NM_001197242) Human Tagged ORF Clone Lentiviral Particle
UBE2C, CT (Ubiquitin-conjugating Enzyme E2 C, Ubiquitin-protein Ligase C, Ubiquitin Carrier Protein C, UbcH10) (APC) discontinued