Thrombin inhibitor 11
Thrombin inhibitor 11 is a thrombin inhibitor, with human and rat Ki values of 65 nM and 10.3 nM, respectively[1].
Product Specifications
UNSPSC
12352005
Target
Thrombin
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/thrombin-inhibitor-11.html
Purity
99.77
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
ClC1=CC=C(C(N[C@H](C(N[C@@H](CC2=CC=CC=C2)C(N3[C@@H](C4)CCC3)=O)=O)CC/C=C/CCCCNC4=O)=O)C=C1
Molecular Formula
C32H39ClN4O4
Molecular Weight
579.13
References & Citations
[1]Merz ML, et al. De novo development of small cyclic peptides that are orally bioavailable. Nat Chem Biol. 2023 Dec 28.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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