Saikosaponin C
Product Specifications
UNSPSC Description
Saikosaponin C is a bioactive component found in radix bupleuri, targets amyloid beta and tau in Alzheimer's disease. Saikosaponin C inhibits the secretion of both Aβ1-40 and Aβ1-42, and suppresses abnormal tau phosphorylation, but shows no effect on BACE1 activity and expression[1].
Target Antigen
Amyloid-β
Type
Natural Products
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/saikosaponin-c.html
Purity
99.65
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O[C@H]([C@@H](O)[C@]([H])(O[C@@H]1C(C)(C)[C@@](CC[C@]2(C)[C@]3([H])C=C[C@@]45[C@@]2(C)C[C@H](O)[C@]6(CO5)[C@@]4([H])CC(C)(C)CC6)([H])[C@]3(C)CC1)O[C@@H]7CO[C@H]8[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O8)[C@@H]7O[C@]9([H])O[C@@H](C)[C@H](O)[C@@H](O)[C@H]9O
Molecular Weight
927.12
References & Citations
[1]Lee TH1, et al. A potential therapeutic effect of saikosaponin C as a novel dual-target anti-Alzheimer agent. J Neurochem. 2016 Mar;136(6):1232-1245.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-N0249/Saikosaponin-C-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-N0249/Saikosaponin-C-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
20736-08-7
Available Sizes
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