FBPase-IN-4
FBPase-IN-4 (Compound 11 n) is a potent FBPase (Fructose-1,6-bisphosphatase) inhibitor with a Ki value of 1.78 μM. FBPase-IN-4 can be used in type 2 diabetes research[1].
Product Specifications
UNSPSC
12352211
Target
FBPase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/fbpase-in-4.html
Smiles
BrCC(NCCC1=CC=C(S(=O)(NC(NC2=CC=C(C3=CC=CC=C3)C=C2)=O)=O)C=C1)=O
Molecular Formula
C23H22BrN3O4S
Molecular Weight
516.41
References & Citations
[1]Cao H, et al. Structure-Guided Design of Affinity/Covalent-Bond Dual-Driven Inhibitors Targeting the AMP Site of FBPase. J Med Chem. 2024 Nov 28;67 (22) :20421-20437.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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