COX-2-IN-38
Product Specifications
UNSPSC Description
COX-2-IN-38 (compound 52*) is a potent inhibitor of COX-2, with the IC50 value of 79.4 nM[1].
Target Antigen
COX
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/cox-2-in-38.html
Solubility
10 mM in DMSO
Smiles
O=C1NC(C2=CC=C(S(=O)(C)=O)C=C2)=NC(NCC3=CC=CS3)=C1
Molecular Weight
361.44
References & Citations
[1]Aurelio Orjales, et al. Hansch analysis of novel pyrimidine derivatives as highly potent and specific COX-2 inhibitors. Bioorg Med Chem. 2008 Mar 1;16(5):2183-99.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-157578/COX-2-IN-38-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-157578/
Clinical Information
No Development Reported
CAS Number
1018480-97-1
Curated Selection
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