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COX-2-IN-38

COX-2-IN-38 (compound 52*) is a potent inhibitor of COX-2, with the IC50 value of 79.4 nM[1].

Product Specifications

CAS Number

[1018480-97-1]

UNSPSC

12352005

Target

COX

Type

Reference compound

Related Pathways

Immunology/Inflammation

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/cox-2-in-38.html

Solubility

10 mM in DMSO

Smiles

O=C1NC(C2=CC=C(S(=O)(C)=O)C=C2)=NC(NCC3=CC=CS3)=C1

Molecular Formula

C16H15N3O3S2

Molecular Weight

361.44

References & Citations

[1]Aurelio Orjales, et al. Hansch analysis of novel pyrimidine derivatives as highly potent and specific COX-2 inhibitors. Bioorg Med Chem. 2008 Mar 1;16 (5) :2183-99.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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