COX-2-IN-38
COX-2-IN-38 (compound 52*) is a potent inhibitor of COX-2, with the IC50 value of 79.4 nM[1].
Product Specifications
CAS Number
[1018480-97-1]
UNSPSC
12352005
Target
COX
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/cox-2-in-38.html
Solubility
10 mM in DMSO
Smiles
O=C1NC(C2=CC=C(S(=O)(C)=O)C=C2)=NC(NCC3=CC=CS3)=C1
Molecular Formula
C16H15N3O3S2
Molecular Weight
361.44
References & Citations
[1]Aurelio Orjales, et al. Hansch analysis of novel pyrimidine derivatives as highly potent and specific COX-2 inhibitors. Bioorg Med Chem. 2008 Mar 1;16 (5) :2183-99.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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