FRS2 Recombinant Rabbit Monoclonal Antibody [JE30-77]
Fibroblast growth factor receptor substrate 2 is a protein that in humans is encoded by the FRS2 gene. FRS2 is an 80 kDa membrane-anchored signal transducing adaptor protein (STAP) that links specific activated Receptor Tyrosine Kinases (RTKs) to multiple downstream signaling pathways, most notably the MAPK/ERK, PI3K/AKT/mTOR and PLCγ pathways. It is overexpressed and amplified in several cancer types, including prostate cancer.
Product Specifications
CAS Number
9000-83-3
Product Name Alternative
Abbreviation
FRS2
Swiss Prot
Q8WU20 Human
Cellular Locus
Endomembrane system.
Host
Rabbit
Species Reactivity
Human
Immunogen
Recombinant protein within Human FRS2 aa 91-240 / 508.
Isotype
IgG
Clone
JE30-77
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, FC
Positive Control
HeLa cell lysate, A549 cell lysate, HEK-293 cell lysate, NCI-H441 cell lysate, MCF7 cell lysate, HeLa.
Concentration
1 mg/mL
Dilution
WB: 1:1,000 ;FC: 1:500-1:1,000
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 57 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes
Frequently Asked Questions
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