Human CD32a (131H) (Luc) Jurkat Reporter Cell
ADCP is the mechanism by which antibody-opsonized target cells activate the FcγRs on the surface of macrophages to induce phagocytosis, resulting in internalization and degradation of the target cell through phagosome acidification. ADCP is mediated by FcγIIa (CD32a) -activated macrophages leading to augmented phagocytosis.
Product Specifications
Background
ADCP is the mechanism by which antibody-opsonized target cells activate the FcγRs on the surface of macrophages to induce phagocytosis, resulting in internalization and degradation of the target cell through phagosome acidification. ADCP is mediated by FcγIIa (CD32a) -activated macrophages leading to augmented phagocytosis.
Host
Jurkat
Origin Species
Human
Target
Fc gamma RIIA / CD32a
Tag
Luc
Applications
• Determination of ADCP activity induced by antibodies.
Format
Liquid
Shipping Conditions
Dry ice
Storage Conditions
Frozen in liquid nitrogen
Package Size
1Vial*2
Product Datasheet
Https://www.acrobiosystems.com/static/main/products/pdf/ds/SCJUR-STF069.pdf
Species
Human
Curated Selection
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