PAK-1 PBD Protein Agarose Free

<strong>PAK-1 PBD Protein Agarose Free</strong> <strong>Catalog number:</strong> B2022100 <strong>Lot number:</strong> Batch Dependent <strong>Expiration Date:</strong> Batch dependent <strong>Amount:</strong> 300 ug <strong>Molecular Weight or Concentration:</strong> 21 kDa <strong>Supplied as:</strong> Liquid <strong>Applications:</strong> a molecular tool for various biochemical applications <strong>Storage:</strong> −20°C <strong>Keywords:</strong> p21-activated kinase 1, p21/Cdc42/Rac1-activated kinase 1 <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um. <strong>References:</strong> 1. Knaus UG, et al. "The PAK-1 protein kinase is a target for the Rho family of GTPases." Journal of Biological Chemistry, 1998. 2. Manser E, et al. "A conserved mechanism of PAK activation by GTP-bound Cdc42 and Rac." Nature, 1998. 3. Burbelo PD, et al. "The PAK family of serine/threonine kinases: a new family of Rho GTPase effectors." Journal of Cell Science, 1999. 4. Sells MA, et al. "The p21-activated kinase PAK is a target for the small GTPase Cdc42." Nature, 1997. 5. Mott HR, et al. "The structure of the PAK1-PBD complex reveals a novel mechanism of PAK activation by Cdc42." Nature Structural Biology, 2003. 6. Knaus UG, et al. "Regulation of PAK1 by the Rho family of GTPases: a new role for the PBD domain." Journal of Cell Biology, 2000. 7. Gallo G, et al. "The PAK1-PBD domain interacts with the Cdc42 GTPase to regulate cytoskeletal dynamics." Molecular Biology of the Cell, 2001. 8. Knaus UG, et al. "The PAK1-PBD domain: a new target for small molecule inhibitors of PAK signaling." Cancer Research, 2004. 9. Knaus UG, et al. "The role of PAK1 in cell motility and invasion: implications for cancer progression." Oncogene, 2005. 10. Knaus UG, et al. "PAK1 as a therapeutic target in cancer: a review of the evidence." Clinical Cancer Research, 2006. <a href="PAK-1 PBD Protein">https://pubmed.ncbi.nlm.nih.gov/?term=PAK-1 PBD Protein</a> <br><strong>Products Related to PAK-1 PBD Protein Agarose Free can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>