U-0521
U-0521 is the inhibitor of the catechol-O-methyltransferase (COMT) . U-0521 has the potential for the research of Parkinson's disease[1].
Product Specifications
CAS Number
5466-89-7
UNSPSC
12352005
Hazard Statement
H302, H312, H332
Target
COMT
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease; Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/u-0521.html
Purity
98.67
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CC(C(C1=CC=C(C(O)=C1)O)=O)C
Molecular Formula
C10H12O3
Molecular Weight
180.20
Precautions
H302, H312, H332
References & Citations
[1]Reches A, et al. Effect of 3',4'-dihydroxy-2-methyl-propriophenone (U-0521) on catechol-O-methyltransferase activity and on DOPA accumulation in rat red blood cells and corpus striatum. Biochem Pharmacol. 1982;31 (21) :3415-3418.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
LY419428 100 µg
Cytokeratin 19 (KRT19) (NM_002276) Human Over-expression Lysate
Sign In for Pricing
View Details