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U-0521

U-0521 is the inhibitor of the catechol-O-methyltransferase (COMT) . U-0521 has the potential for the research of Parkinson's disease[1].

Product Specifications

CAS Number

5466-89-7

UNSPSC

12352005

Hazard Statement

H302, H312, H332

Target

COMT

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease; Neuronal Signaling

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/u-0521.html

Purity

98.67

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

CC(C(C1=CC=C(C(O)=C1)O)=O)C

Molecular Formula

C10H12O3

Molecular Weight

180.20

Precautions

H302, H312, H332

References & Citations

[1]Reches A, et al. Effect of 3',4'-dihydroxy-2-methyl-propriophenone (U-0521) on catechol-O-methyltransferase activity and on DOPA accumulation in rat red blood cells and corpus striatum. Biochem Pharmacol. 1982;31 (21) :3415-3418.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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