KRAS G12D inhibitor 22
KRAS G12D inhibitor 22 (compound 6) is a inhibitor of KRAS mutation. KRAS G12D inhibitor 22 has high activity (IC50[1].
Product Specifications
UNSPSC
12352005
Target
Ras
Type
Reference compound
Related Pathways
GPCR/G Protein; MAPK/ERK Pathway
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/kras-g12d-inhibitor-22.html
Solubility
10 mM in DMSO
Smiles
OC1=CC(C=CC(F)=C2C#C)=C2C(C3=NC=C4C(N=C(OCC5(CCC6)N6CC7(C(F)(F)C7)C5)N=C4N8C[C@H]9N[C@H](CC9)C8)=C3F)=C1
Molecular Formula
C35H32F4N6O2
Molecular Weight
644.66
References & Citations
[1]Huang Qi, et al. Pyrimidine fused ring compound, preparation method therefor, and use thereof.WO2024061365. 2023-09-22
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
K-Ras
Frequently Asked Questions
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