CYP11B2-IN-2
CYP11B2-IN-2 (Compound 10k) is an inhibitor for enzyme aldosterone synthase CYP11B2 with an IC50 of 0.3 nM. CYP11B2-IN-2 CYP11B-IN-2 is labeled with 18F and can be used as a positron emission tomography (PET) tracer for the diagnosis of primary aldosteronism[1].
Product Specifications
CAS Number
2241573-22-6
UNSPSC
12352005
Target
Cytochrome P450
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/cyp11b2-in-2.html
Smiles
FC1=CC(C2=CC(C3(C)OCCO3)=CN=C2)=CC=C1C#N
Molecular Formula
C16H13FN2O2
Molecular Weight
284.29
References & Citations
[1]Maier P, et al., Fluorinated aldosterone synthase (CYP11B2) -inhibitors for differential diagnosis between bilateral and unilateral conditions of primary aldosteronism. Bioorg Med Chem Lett. 2023 Nov 15;96:129501.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CYP11
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
