CD2 Antibody / Lymphocyte Function Antigen 2 / LFA-2
CD2 is mainly present on the surface of mature T cells and NK cell membranes, while B cells are usually not expressed. It can be used to label the diagnosis and study of normal T cells and their associated tumors, such as pre-t cell lymphoma, marginal T cell lymphoma and anaplastic cell lymphoma. CD2 antibody is useful for identification of precursor and mature T-cell lymphomas. Aberrant loss of CD2 in T-cell lymphomas may help to distinguish them from reactive T-cell proliferations.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1-2 µg/mL, Immunohistochemistry (FFPE) : 1-2 µg/mL
UniProt
P06729
Host
Mouse
Reactivity
Human
Immunogen
A recombinant fragment from the human protein was used as the immunogen for the CD2 antibody.
Clonality
Monoclonal
Isotype
IgG1 k
Clone
LFA2/7106
Applications
WB, IHC-P
Purity
Protein A/G affinity
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Reconstitution
Aliquot the CD2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This CD2 antibody is available for research use only.
Storage Conditions
Aliquot the CD2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05% sodium azide
Applications Notes
Optimal dilution of the CD2 antibody should be determined by the researcher.
Location
Cell surface
Image Legend
Western blot testing of human Jurkat cell lysate using CD2 antibody (clone LFA2/7106) . Expected molecular weight ~47 kDa.
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