Recombinant PHOX2B Antibody
Paired homeobox protein 2B (PHOX2B) is a transcription factor located on chromosome 4p13, which is essential for the formation of autonomic ganglia in the autonomic nervous system. PHOX2B is expressed in neuroblastoma, brain and adrenal glands. PHOX2B deficiency can lead to susceptibility to congenital central hypoventilation syndrome (CCHS) and neuroblastoma type 2 (NBLST2) .
Product Specifications
CAS Number
9000-83-3
Specifications
Immunohistochemistry (FFPE) : 1-2 µg/mL
UniProt
Q99453
Host
Rabbit
Reactivity
Human
Immunogen
A human PHOX2B partial protein was used as the immunogen for the recombinant PHOX2B antibody.
Clonality
Recombinant Monoclonal
Isotype
IgG κ
Clone
PHOX2B/7161R
Type
Recombinant
Applications
IHC-P
Purity
Protein A/G affinity
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Reconstitution
Aliquot the recombinant PHOX2B antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This recombinant PHOX2B antibody is available for research use only.
Storage Conditions
Aliquot the recombinant PHOX2B antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05% sodium azide
Applications Notes
Optimal dilution of the recombinant PHOX2B antibody should be determined by the researcher.
Location
Nucleus
Image Legend
Frequently Asked Questions
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