Lymphocyte Function Antigen 2 Antibody / LFA-2 / CD2

CD2 is mainly present on the surface of mature T cells and NK cell membranes, while B cells are usually not expressed. It can be used to label the diagnosis and study of normal T cells and their associated tumors, such as pre-t cell lymphoma, marginal T cell lymphoma and anaplastic cell lymphoma. CD2 antibody is useful for identification of precursor and mature T-cell lymphomas. Aberrant loss of CD2 in T-cell lymphomas may help to distinguish them from reactive T-cell proliferations.

Product Specifications

CAS Number

9007-83-4

Specifications

Immunohistochemistry (FFPE) : 1-2 µg/mL

UniProt

P06729

Host

Mouse

Reactivity

Human

Immunogen

A recombinant fragment from the human CD2 protein was used as the immunogen for the Lymphocyte Function Antigen 2 antibody.

Clonality

Monoclonal

Isotype

IgG2b κ

Clone

LFA2/7104

Applications

IHC-P

Purity

Protein A/G affinity

Format

Purified

Buffer

0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide

Reconstitution

Aliquot the Lymphocyte Function Antigen 2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This Lymphocyte Function Antigen 2 antibody is available for research use only.

Storage Conditions

Aliquot the Lymphocyte Function Antigen 2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05% sodium azide

Applications Notes

Optimal dilution of the Lymphocyte Function Antigen 2 antibody should be determined by the researcher.

Location

Cell surface

Image Legend

IHC staining of FFPE human spleen tissue with CD2 antibody (clone LFA2/7104) . HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.