SCFR Antibody / c-Kit / CD117
C-Kit, also called CD117, SCFR and Stem Cell Factor Receptor is found on a wide variety of tumor cells including follicular and papillary carcinoma of thyroid, adenocarcinomas from endometrium, lung, ovary, pancreas, and breast as well as malignant melanoma, endodermal sinus tumor, and small cell carcinoma. However, anti-SCFR has been particularly useful in differentiating gastrointestinal stromal tumors from Kaposi s sarcoma, tumors of smooth muscle origin, fibromatosis, and neural tumors of the GI tract. Anti-SCFR is also useful in recognizing myeloblasts in bone marrow biopsy and clot section.
Product Specifications
CAS Number
9007-83-4
Specifications
ELISA: 2-4 µg/mL (order Ab without BSA for coating), Immunohistochemistry (FFPE) : 2-4 µg/mL
UniProt
P10721
Host
Mouse
Reactivity
Human
Immunogen
A portion of amino acids 50-250 from the human protein was used as the immunogen for the SCFR antibody.
Clonality
Monoclonal
Isotype
IgG1 k
Clone
C117/7119
Applications
ELISA, IHC-P
Purity
Protein A/G affinity
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Reconstitution
Aliquot the SCFR antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This SCFR antibody is available for research use only.
Storage Conditions
Aliquot the SCFR antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05% sodium azide
Applications Notes
Optimal dilution of the SCFR antibody should be determined by the researcher.
Location
Cell surface, cytoplasm
Image Legend
Documents
Frequently Asked Questions
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