Fibrillin-1 Antibody / FBN1

Fibrillin-1 / FBN1 is an extracellular matrix glycoprotein that serves as a structural component of calcium-binding microfibrils. These microfibrils provide force-bearing structural support in elastic and non-elastic connective tissue throughout the body. Mutations in this gene are associated with Marfan syndrome.

Product Specifications

CAS Number

9007-83-4

Specifications

ELISA: order antibody without BSA for coating, Immunohistochemistry (FFPE) : 1-2 µg/mL

UniProt

P35555

Host

Mouse

Reactivity

Human

Immunogen

A portion of amino acids 330-476 was used as the immunogen for the Fibrillin-1 antibody.

Clonality

Monoclonal

Isotype

IgG1 k

Clone

FBN1/6933

Applications

ELISA, IHC-P

Purity

Protein A/G affinity

Format

Purified

Buffer

1 mg/ml in 1X PBS; BSA free, sodium azide free

Reconstitution

Aliquot the Fibrillin-1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This Fibrillin-1 antibody is available for research use only.

Storage Conditions

Aliquot the Fibrillin-1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

1 mg/mL in 1X PBS; BSA free, sodium azide free

Applications Notes

Optimal dilution of the Fibrillin-1 antibody should be determined by the researcher.

Location

Extracellular matrix

Image Legend

IHC staining of FFPE human colon carcinoma with Fibrillin 1 antibody (clone FBN1/6933) . HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.