POU5F1 Antibody / OCT4
OCT4/POU5F1 is a member of the POU family of transcription factors, involved in the regulation of pluripotency during normal development and is detectable in embryonic stem and germ cells. It is a key regulator of self-renewal in embryonic stem cells; its expression is potentially correlated with tumorigenesis and can affect tumor recurrence or resistance to therapies. OCT4/POU5F1 is expressed in undifferentiated pluripotent cells, germ cells in ovary and testis.
Product Specifications
CAS Number
9000-83-3
Specifications
Immunohistochemistry (FFPE) : 1-2 µg/mL
UniProt
Q01860
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant fragment from the human protein was used as the immunogen for the POU5F1 antibody.
Clonality
Recombinant Monoclonal
Isotype
IgG κ
Clone
OCT4/6847R
Type
Recombinant
Applications
IHC-P
Purity
Protein A/G affinity
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Reconstitution
Aliquot the POU5F1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This POU5F1 antibody is available for research use only.
Storage Conditions
Aliquot the POU5F1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05% sodium azide
Applications Notes
Optimal dilution of the POU5F1 antibody should be determined by the researcher.
Location
Nucleus
Image Legend
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
