Poliovirus Receptor Antibody / PVR

CD155 (cluster of differentiation 155) also known as the poliovirus receptor is a protein that in humans is encoded by the PVR gene. The protein encoded by this gene is a transmembrane glycoprotein belonging to the immunoglobulin superfamily. The external domain mediates cell attachment to the extracellular matrix molecule vitronectin, while its intracellular domain interacts with the dynein light chain Tctex-1/DYNLT1. The gene is specific to the primate lineage, and serves as a cellular receptor for poliovirus in the first step of poliovirus replication. Multiple transcript variants encoding different isoforms have been found for this gene.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 0.5-1 µg/mL, Immunohistochemistry (FFPE) : 2-5 µg/mL, Flow cytometry: 1-3ug/million cells

UniProt

P15151

Host

Mouse

Reactivity

Human, Mouse

Immunogen

Recombinant human protein (amino acids D28-E331) was used as the immunogen for the Poliovirus Receptor antibody.

Clonality

Monoclonal

Isotype

IgG2a

Clone

5I13D1

Applications

WB, IHC-P, FACS

Purity

Antigen affinity purified

Format

Antigen affinity purified

Buffer

Lyophilized from 1X PBS with 2% Trehalose

Reconstitution

After reconstitution, the Poliovirus Receptor antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Limitations

This Poliovirus Receptor antibody is available for research use only.

Storage Conditions

After reconstitution, the Poliovirus Receptor antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Formulation

0.5 mg/mL if reconstituted with 0.2ml sterile DI water

Applications Notes

Optimal dilution of the Poliovirus Receptor antibody should be determined by the researcher.

Image Legend

IHC staining of FFPE human endometrial cancer tissue with Poliovirus Receptor antibody. HIER: boil tissue sections in pH8 EDTA for 20 min and allow to cool before testing.