ARN2966
ARN2966 is a potent, orally active and cross the blood-brain barrier amyloid precursor protein (APP) translation modulator. ARN2966 shows anti-A aggregation and neuroprotective properties. ARN2966 has the potential for the research of alzheimer's disease[1].
Product Specifications
CAS Number
[102212-26-0]
UNSPSC
12352005
Hazard Statement
H302
Target
Amyloid-β
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ARN2966.html
Purity
98.78
Solubility
DMSO : 110 mg/mL (ultrasonic)
Smiles
OC1=CC=CC=C1NCC2=NC=CC=C2
Molecular Formula
C12H12N2O
Molecular Weight
200.24
Precautions
H302
References & Citations
[1]yodeji Asuni, et al. An APP translation modulator ARN2966 reduces BETA-AMYLOID deposition and prevents memory deficits in ALZHEIMER'S DISEASE transgenic mice. Alzheimer's & Dementia: The Journal of the Alzheimer's Association. 2012.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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