Intercellular adhesion molecule 1 Antibody / ICAM1

CD54, also known as ICAM-1 and Intercellular adhesion molecule-1 (ICAM1) is a ligand for lymphocyte function-associated (LFA) antigens. ICAM-1 is an integral membrane protein, a member of the immunoglobulin superfamily, and a ligand for LFA-1, a beta 2 leukocyte integrin. This protein is the major human rhinovirus receptor. The ICAM1 gene is mapped to human chromosome 19. In humans, lymphocyte adhesion to cells is mediated by the protein heterodimer CD11a/CD18 (Leu-CAMa, LFA-1) and its ligand CD54 (ICAM-1) .

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 0.5-1 µg/mL, Immunohistochemistry (FFPE) : 2-5 µg/mL, Flow cytometry: 1-3ug/million cells

UniProt

P05362

Host

Mouse

Reactivity

Human

Immunogen

Recombinant human protein (amino acids Q28-R268) was used as the immunogen for the Intercellular adhesion molecule 1 antibody.

Clonality

Monoclonal

Isotype

IgG1

Clone

6F2C3

Applications

WB, IHC-P, FACS

Purity

Antigen affinity purified

Format

Antigen affinity purified

Buffer

Lyophilized from 1X PBS with 2% Trehalose

Reconstitution

After reconstitution, the Intercellular adhesion molecule 1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Limitations

This Intercellular adhesion molecule 1 antibody is available for research use only.

Storage Conditions

After reconstitution, the Intercellular adhesion molecule 1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Formulation

0.5 mg/mL if reconstituted with 0.2ml sterile DI water

Applications Notes

Optimal dilution of the Intercellular adhesion molecule 1 antibody should be determined by the researcher.

Image Legend

IHC staining of FFPE human rectal moderately differentiated adenocarcinoma tissue with Intercellular adhesion molecule 1 antibody. HIER: boil tissue sections in pH8 EDTA for 20 min and allow to cool before testing.