MASPIN Antibody / SERPINB5

SERPINB5 is also known as PI5 or maspin. Maspin (mammary serine protease inhibitor) is a protein that in humans is encoded by the SERPINB5 gene. Maspin is expressed in the skin, prostate, testis, intestine, tongue, lung, and the thymus. Maspin is a member of the serpin superfamily of serine protease inhibitors.[1] The primary function of most members of this family is to regulate the breakdown of proteins by inhibiting the catalytic activity of proteinases. Through this mechanism of action, serpins regulate a number of cellular processes includingphagocytosis, coagulation, and fibrinolysis.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 0.5-1 µg/mL, Immunohistochemistry (FFPE) : 2-5 µg/mL, Flow cytometry: 1-3ug/million cells

UniProt

P36952

Host

Mouse

Reactivity

Human

Immunogen

Recombinant human MASPIN protein (amino acids M1-A350) was used as the immunogen for the MASPIN antibody.

Clonality

Monoclonal

Isotype

IgG2a

Clone

7G4E1

Applications

WB, IHC-P, FACS

Purity

Antigen affinity purified

Format

Antigen affinity purified

Buffer

Lyophilized from 1X PBS with 2% Trehalose

Reconstitution

After reconstitution, the MASPIN antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Limitations

This MASPIN antibody is available for research use only.

Storage Conditions

After reconstitution, the MASPIN antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Formulation

0.5 mg/mL if reconstituted with 0.2ml sterile DI water

Applications Notes

Optimal dilution of the MASPIN antibody should be determined by the researcher.

Image Legend

IHC staining of FFPE human tonsil tissue with MASPIN antibody. HIER: boil tissue sections in pH8 EDTA for 20 min and allow to cool before testing.

Curated Selection

Ask

View Details

MBS2091551-04 1 mL

Biotin-Linked Polyclonal Antibody to Matrix Metalloproteinase 3 (MMP3)

Ask

View Details