Piretanide

Piretanide is an oral active, relatively safe and effective diuretic. Piretanide has the potential for the research of congestive heart failure with a potential advantage of having potassium-sparing properties. Piretanide can also be used for the research of hypertension[1][2].

Product Specifications

CAS Number

[55837-27-9]

UNSPSC

12352005

Hazard Statement

H302-H312-H332

Target

NKCC

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/piretanide.html

Purity

99.87

Solubility

DMSO : 250 mg/mL (ultrasonic)

Smiles

O=C(C1=CC(S(=O)(N)=O)=C(C(N2CCCC2)=C1)OC3=CC=CC=C3)O

Molecular Formula

C17H18N2O5S

Molecular Weight

362.40

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P363-P501

References & Citations

[1]Carda-Broch S, et al. Analysis of urine samples containing cardiovascular drugs by micellar liquid chromatography with fluorimetric detection. J Chromatogr Sci. 1999;37 (4) :93-102. |[2]Sherman LG, et al. Piretanide, a potent diuretic with potassium-sparing properties, for the treatment of congestive heart failure. Clin Pharmacol Ther. 1986;40 (5) :587-594.