Myr-TAT-CBD3
Myr-TAT-CBD3 is CRMP2-CaV2.2 interaction inhibitor. Myr-tat-CBD3 can significantly attenuate carrageenan-induced thermal hypersensitivity and reverse thermal hypersensitivity induced in a rat model of postoperative pain. Myr-TAT-CBD3 can be used to study inflammation and postoperative pain[1].
Product Specifications
UNSPSC
12352209
Target
Calcium Channel
Type
Peptides
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/myr-tat-cbd3.html
Solubility
10 mM in DMSO
Smiles
CCCCCCCCCCCCCC(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](C)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC(C)C)C(N[C@@H](C)C(N[C@H](C(N[C@@H](CC(C)C)C(N[C@H](C(NCC(N[C@H](C(N1CCC[C@H]1C(N[C@H](C(NCC(N[C@@H](CC(C)C)C(O)=O)=O)=O)CCCNC(N)=N)=O)=O)C(C)C)=O)=O)CCCNC(N)=N)=O)=O)CCC(O)=O)=O)=O)=O)CCCNC(N)=N)=O)CO)=O)CCCNC(N)=N)=O)=O)CCCNC(N)=N)=O)CCCNC(N)=N)=O)CCCNC(N)=N)=O)CCC(N)=O)=O)CCCNC(N)=N)=O)CCCNC(N)=N)=O)CCCCN[H])=O)CCCCN[H])=O)CCCNC(N)=N)=O)=O)CC2=CC=C(C=C2)O)=O
Molecular Formula
C148H269N59O33
Molecular Weight
3403.09
References & Citations
[1]François-Moutal L, et al. A membrane-delimited N-myristoylated CRMP2 peptide aptamer inhibits CaV2.2 trafficking and reverses inflammatory and postoperative pain behaviors. Pain. 2015 Jul;156 (7) :1247-1264.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
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