(S) -CPP (sodium)
(S) -CPP sodium serves as an inhibitor of the branched-chain α-ketoacid dehydrogenase complex (BCKDC) kinase, commonly referred to as BDK or keto acid dehydrogenase kinase. As a negative regulator of BCKDC activity, the inhibition of BDK by (S) -CPP (with an IC50 of 6.3 μM) results in the activation of the complex and a notable decrease in plasma levels of leucine/isoleucine and valine in wild-type mice.
Product Specifications
CAS Number
[194979-70-9]
UNSPSC
12352005
Target
Endogenous Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/s-cpp-sodium.html
Smiles
O=C(O[Na])[C@@H](Cl)CC1=CC=CC=C1
Molecular Formula
C9H8ClNaO2
Molecular Weight
206.60
References & Citations
[1]Erne, D., et al.Helvetica Chimica Acta1980|[2]Paper-Based Electronic Tongue
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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